Physicians’ Select Female Sexual Enhancement Cream For Women
Physicians Select Herbal Supplements – offer a female sexual enhancement cream that has been derived from a multitude of laboratory tests and clinical studies along with advise from licensed physicians, pharmacists, nutritionists, PhD's, chemists and herbal specialists All of our raw materials must pass stringent quality controls before they are utilized. We use only those precursor materials that are of the highest quality All our herbal supplements are guaranteed with unconditional full refund of the product price if you are not completely satisfied with the results.
The following are the ingredients in the Physicians’ Select Female Sexual Enhancement Cream:
Source - L Arginine - is an essential amino acid (the body cannot create the amino acid on its own it must be ingested). Arginine is found in many foods, including dairy products, meat, fish and poultry.
As a woman is sexually stimulated, the brain signals the pudendal and the clitoral nerve. Next the Nitric Oxide Synthase System is activated. The Nitric Oxide Synthase System converts the available L-Arginine into nitric oxide. Nitric Oxide draws blood into the area causing the clitoris to become aroused and highly sensitive. Orgasm occurs when a fully aroused clitoris is properly stimulated. The body naturally produces nitric oxide, a potent signal molecule for circulation. Enhanced nitric oxide production in the female sexual organs, allows for improved engorgement and lubrication of clitoris and the vagina.
The role of nitric oxide in controlling blood flow was only recently discovered in 1998 resulting in a Nobel Prize for scientific discovery. From this discovery, the researchers at Physicians’ Select further discovered that the application of L-Arginine, in a specially compounded transdermal solution results in the production of a natural and optimal female sexual response. Physicians’ Select Sexual Enhancement Gel also contains a Menthol preparation. Research as shown that the application of menthol promotes the absorption of the Arginine. Acting to relax and dilate the skin cells, menthol allows Arginine into the blood stream and nerves faster, thus, increasing blood flow to the clitoris and stimulating nerve endings. The result a heightened female sexual response including intense female orgasms.
Below is a description of how the male and female genitalia are very similar including a reference to clinical studies that suggest the erection process of the excited female clitoris is very similar to the erection of the penis.
Research has shown that lubrication similar to the ingredients found in Physicians' Select Female Enhancement Gel of the vaginal epithelium and the clitoris is associated with increased blood flow. J. R. Berman and I. Goldstein. Female Sexual Dysfunction. Urology Clinical North America 28 (2):405-416, 2001.
From the embryology illustrations below the following text, one can visualize the similarities the female and male genitalia. Additional studies suggests that the nitric oxide and the cGMP mediates the arterial smooth muscle relaxation of the clitoris in the same manner as that found in the male penis. When the female experiences sexual stimulation, nitric oxide is synthesized from L-arginine in the nerve and vascular tissue of the clitoris. Nitric oxide stimulates the release of guanylate cyclase that converts GTP to cGMP. cGMP relaxes the smooth muscles of the arterioles in the clitoral tissues resulting in vasocongestion or an erection of clitoris promoting intense female orgasms.
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Orgasm occurs when a fully aroused clitoris is properly stimulated. C. M. Meston and P. F. Frohlich. The Neurobiology of Sexual Function. Arch Gen.Psychiatry 57 (11):1012-1030, 2000. A. L. Burnett, D. C. Calvin, R. I. Silver, D. S. Peppas, and S. G. Docimo. Immunohistochemical Description of Nitric Oxide Synthase Isoforms in Human Clitoris. J Urol 158 (1):75-78, 1997.
Precautions and/or adverse effects:
Individuals with preexisting medical conditions should consult with their physician particularly if they are taking prescription or over-the-counter-medications or supplements. Women who are pregnant or breast feeding should also consult with there physician prior to taking any new supplements. Although there is very a limited amount of Arginine systemically absorbed via the transdermal delivery of Physicians' Select Female Enhancement Cream individuals should still be cautious if they have any of the following medical conditions:
- Low blood pressure
- Liver or Kidney disease
- Individuals on blood thinners
- Psychological conditions, such as, psychosis
- Diabetics and borderline diabetics
- Individuals who have not completed their bone growth i.e. children and/or teenagers
- Individuals with acute or chronic viral conditions i.e. Epstein-Barr Virus (EBV),
- (CMV), Herpes Virus, Human Immunodeficiency Virus (HIV)
There are very few side effects associated with the supplemental use of the herb. Again, these reported side effects generally occur with the oral consumption of Arginine and not via the transdermal application to the clitoris.
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Sources - Menthol - is a naturally occurring monocyclic terpene (any of various unsaturated hydrocarbons, C10H16, found in essential oils and oleoresins of plants such as conifers and used in organic syntheses) found in the oils of the mint tree Mentha arvensis. Menthol is well known for its cooling effects and its mint flavor which are used in liniments, antipruritic agent, mouthwashes, nasal sprays, expectorants, cough drops, etc.
Physiology - Transdemal delivery of medication and/or herbal supplements depends on the controlled rapid molecular transport across the skin. Clinical studies have shown that menthol can dramatically increase the transdermal delivery of medications and/or herbal supplements i.e. L Arginine that results in the increase of blood flow to the clitoris accompanied by subsequent enhanced orgasms.
The skin is made up of three layers, epidermis, dermis and the subcutaneous layer:
Epidermis - the tough outer protective layer of the skin that contains the melanin, pigment that gives the skin color; keratinocytes, which produce the basic component of the nails, keratin and the langerhans cells, which help to protect the body from infection.
Dermis - is the middle layer of the skin that provides nourishment to the epidermal layer. The dermis is the thickest layer that comprises a tight mesh of elastin and collagen fibers. Collagen is responsible for the structural support of the skin while elastin provides resilience. The dermis also contains nerve endings, blood vessels, and lymph nodes.
Subcutaneous layer - is the innermost layer of the skin that consists mainly of adipocytes (fat cells) connective tissue and blood vessels. The subcutaneous fat cells serve as a heat insulator to maintain body temperature while providing a sort of shock absorber protecting underlying structures. Sweat glands also originate in this subcutaneous layer.
The epidermis is made up of 5 layers. the primary barrier of the skin to transdermal permeation of medications and/or herbal supplements is a layer known as the stratum corneum.
Listed below are the five layers of the skin:
- Stratum Corneum - is the outermost layer consisting of closely packed, flat, dead cells that are constantly replaced secondary to abrasion.
- Stratum Lucidem - is a clear band consisting of mostly of packed cells with indistinct outer boundaries Stratum Granulosum - is the granular layer made up of keratinocytes. These cells provide a barrier between the host and the environment in order to prevent the entry of toxic substances from the environment and the loss of important constituents fromthe host.)
- Sratum Spinosum - is known as the "prickel cell: layer because when these cells are seen under the microscope they look prickly secondary to the cells appearing to have extensions connected to other cells.
- Stratum Basale - represents the bottom or deepest layer of the epidermis These cells mature and become more specialized as they move toward the surface of the skin. Melanin is formed here to protect against ultraviolet radiation.
The majority of herbal companies develop their herbal ointments, gels and lotions without addressing the concept of the transdermal (across the dermis of the skin) delivery process. Companies can blend a wide variety of beneficial herbal components in their formulas, however, if these ingredients cannot get past the protective layers of the skin they will produce no effects. Physicians' Select has researched and addressed the problem of transdermal application, specifically developing a synergistic (when two herbal ingredients together produce a greater effect than the two individual ingredients can produce on their own i.e. 1+1 = 3) blend of herbal ingredients that can penetrate the dermal layer of the skin.
In addition, many herbal companies develop only oral products to improve the stimulation of the clitoris. Physicians' Select understands that there are many facets to the sexual response in women, therefore, we have developed two products a gel specifically designed for direct application to the clitoris and an oral formula to increase libido and enhance the overall sexual response.
Physicians' Select Female Sexual Enhancement Cream by developing a transdermal cream that can penetrate the dermal layer of the skin of the clitoris promotes enhanced erections in the following ways:
- Enhanced efficacy (capacity to produce a desired effect)
- Improved convenience and compliance
- Decreased side effects, application easy to terminate if side effects do occur
- Avoids "peak and valley" effects associated with oral supplements
- Reduce dosing via the transdermal application, active ingredients bypass first pass effect through the gastrointestinal tract
Research as shown that the application of menthol when combined with other topical transdermal arginine actual promotes the absorption of the Arginine. Menthol acting to relax and dilate the skin cells, allows Arginie into the blood stream and nerves faster, thus, increasing blood flow to the clitoris and stimulates nerve endings. The warm tingling sensation secondary to the application of menthol to the clitoris also promotes the sexual response resulting in an increase in vaginal lubrication and a release of the all important nitric oxide (please refer to the physiology section for a detailed explanation of how an increase in nitric oxide promotes an intensified orgasmic response).
According to a study cited in the the Journal of Pharmaceutical Sciences the use of Menthol increases skin flux up to eight times the base line enabling transdermal medications to be absorbed more readily. Kaplun-Frischoff Y. Touitou E. Testosterone skin permeation enhancement by menthol through formation of eutectic with drug and interaction with skin lipids. Journal of Pharmaceutical Sciences. 86(12):1394-9, 1997 Dec.
Modern day uses:
Today, Menthol is prescribed by physicians and herbal specialist for the following:
- Transdermal agent - blended with other topical ointments, gels and lotions in order to promote absorption.
- Local anesthetic - used in over-the-counter supplements for the relief of throat irritation, muscle aches, arthritic pain, etc.
- Flavoring - used as a flavoring agent in a wide variety of products from cigarettes to mouthwash.
Precautions and/or adverse effects:
Individuals with preexisting medical conditions should consult with their physician particularly if they are taking prescription or over-the-counter-medications or supplements. Women who are pregnant or breast feeding and children should also consult with there physician prior to taking any new supplements.
Physicians’ Select Female Enhancement Cream also contains the following proprietary blend of the following ingredients.:
- De-ionized water
- Propylene Glycol
- Hydroxyethyl Cellulose
- Methyl Paraben
- Propyl Paraben
Please note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. The information should not be construed to indicate that the use of the product is appropriate, safe, or effective for each individuals use.
Order Physicians' Select Female Sexual Enhancement Cream the sexual enhancement cream with the most active ingredients to enhance female orgasms (click here for more information).
Back to the list of female sexual enhancement cream ingredients
Female Sexual Enhancement References:
Berman J. R. and Goldstein I. . Female sexual dysfunction. Urol Clin North Am 28 (2):405-416, 2001. Borins M. The dangers of using herbs: what your patients need to know. Postgrad Med.1998;104(1):91-100.
Burnett, D. C. Calvin, R. I. Silver, D. S. Peppas, and S. G. Docimo. Immunohistochemical description of nitric oxide synthase isoforms in human clitoris. J Urol 158 (1):75-78, 1997.
Cellek S., Moncada S., Nitrergic neurotransmission mediates the non-adrenergic non-cholinergic responses in the clitoral corpus cavernosum of the rabbit. Br J Pharmacol. 125 (8):1627-1629, 1998.
Ismailoglu U. Burcin, I. Sahin-Erdemli, and M. Ilhan. L-arginine-induced relaxation of the rat isolated penile bulb. Eur.J Pharmacol. 435 (1):113-117, 2002.
Kaplan HS. The illustrated manual of sex therapy. 2d ed. New York: Brunner/Mazel 1987:72-98.
Kaplun-Frischoff Y. Touitou E. Testosterone skin permeation enhancement by menthol through formation of eutectic with drug and interaction with skin lipids. Journal of Pharmaceutical Sciences. 86(12):1394-9, 1997 Dec.
LuBec, B., et el, Free Radical Biology & Medicine (1997) 22: 1-2: 355-357
MacAllister, R.J., et al., Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase. Br J Pharmacol, 1996. 119(8): p. 1533-40.
Meston R. C. M., Frohlich P. F.. The neurobiology of sexual function. Arch Gen.Psychiatry 57 (11):1012-1030, 2000. Drugs that cause sexual dysfunction: an update. Med Lett Drugs Ther 1992;34:73-8.
Nathorst-Boos J, Wiklund I, Mattsson LA, Sandin K, von Schoultz B. Is sexual life influenced by transdermal estrogen therapy? A double blind placebo controlled study in postmenopausal women. Acta Obstet Gynecol Scand 1993;72:656-60.
Park K, Goldstein I, Andry C, Siroky MB, Krane RJ. Azadzoi KM. Vasculogenic female sexual dysfunction: the hemodynamic basis for vaginal engorgement insufficiency and clitoral erectile dysfunction. Int J Impot Res 1997;9:27-37.
Phillips NA. The clinical evaluation of dyspareunia. Int J Impot Res 1998;10(suppl 2):S117-20
Read S, King M, Watson J. Sexual dysfunction in primary medical care: prevalence, characteristics and detection by the general practitioner. J Public Health Med 1997;19:387-91.
Thorne S, Mullen MJ, Clarkson P, et al: Early endothelial dysfunction in adults at risk from atherosclerosis: different responses to L-arginine. J Am Coll Cardiol 1998 Jul; 32(1): 110-6
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