Phytoestrogens Information

Phytoestrogens, a discussion of the herbal ingredients in Physicians' Select Herbal Breast Enhancement Supplements would not be complete without explaining the importance of Phytoestrogens. The prefix "phyto" is from the Greek prefix "phyton" meaning "plant" hence plant estrogen. Phytoestrogens are a group of naturally occurring compounds that have a chemical structure very similar to estrogen.

Phytoestrogens have shown to be responsible for for the following positive effects:

• Lower incidence of female related cancer i.e. breast, endometrial, uterus
  
• Reduce the risk for stroke
  
• Decrease in the symptoms of menopause
  
• Promote hormone balance resulting in larger firmer breast tissue

Estrogen is a hormone that is necessary for the normal sexual development and growth of the breasts, uterus and ovaries. The hormone plays a significant role in controlling a woman's menstrual cycles and is essential for reproduction. Estrogen also helps maintain the cardiovascular system and prevent osteoporosis a disease in which the bones become extremely porous, subject to fracture, tend to heal slowly and are subject to infection.

Estrogen's access to reproductive tissue i.e. breast and endometrial is controlled by estrogen receptors that act as gatekeepers. Only estrogen or substances with a close structural resemblance to estrogen are permitted to bind. This explains how the similar phytoestrogens can bind to the estrogen receptors and displace the estrogen.

If estrogen is important to the normal growth of the reproductive tissue then why would we want to displace it from the estrogen receptors? Unfortunately, cancer cells also use estrogen to promote their growth. Normal cells grow and die in a controlled fashion. Cancer occurs when normal cells become abnormal and subsequently differentiate and grow without control or structure. Cancer cells usually grow at a rate significantly faster than our normal cells. Some cancer cells have estrogen receptors that are programmed to grow when estrogen binds to these receptor sites.

Excess exposure to estrogen is one of the primary risk factors for developing breast and endometrial cancer, the following situations represent an increased risk for estrogen exposure:

• Age of Menarche (onset of menstruation) - early menarche has consistently been shown to be associated with an increased risk for breast cancer.
  
• First Full Term Pregnancy (age) - women who have not bore any children are at increased risk as compared women who have not had children. The proliferation of breast tissue during the first pregnancy allows the breast tissue to mature, decreasing the risk of cancer.
  
• Lactation - cultural studies have shown that women who commonly breast feed their children have a lower incidence of breast cancer because breast feeding promotes the maturation of the breast cells.
  
• Obesity - being more than 50 pounds overweight, fat tissue can convert other hormones in the body into estrogens).
  
• Age of Menopause - women who enter menopause late in life are at greater risk due to their increased exposure to hormones.

Research has shown that Phytoestrogens, or estrogen that is common in certain plants and herbs can displace the human estrogen and decrease the growth of tumor cells. Studies have revealed a lower incidence and mortality from hormone-dependent cancers in Asian women and men who consume traditional Asian diets, which are rich in herbs that contain Phytoestrogens. Whereas, Asian women who consume western diets have breast cancer rates similar to caucasian women.

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Animal studies have come to the same conclusions, a study of rats found that those exposed to Phytoestrogen while in the uterus or around the time of birth were more resistant to breast cancer. Another study found that high consumption of soy and other legumes (beans) was associated with having half the risk of developing endometrial cancer. Medical researchers now believe that Phytoestrogens may one day replace Tamoxifen and the other estrogen replacement medications.

Phytoestrogens, while they displace the human estrogen, support female hormone levels by exerting an estrogen like effect on the reproductive organs. These Phytoestrogens are an estimated to be 100-500 times less potent in their estrogen effect than human estrogen. They maintain a hormonal balance by acting as anti-estrogen when the body's natural levels are high and they act as human estrogen when levels are low.

Strokes are the third leading cause of death for middle-age and older women. One of the major causes of strokes is compromised of blocked carotid arteries. Phytoestrogens have shown to improve a women's lipid profile to prevent strokes, similar to Premarin without the added risk of cancer.

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Phytoestrogens with their estrogenic like properties also provide an excellent relief from the common symptoms of menopause including the following:

• Night sweats
• Mood swings
• Vaginal dryness
• Sagging breast
• Sexual disinterest
• Weight gain
• Memory and concentration problems
• Depression
• Hot flashes
• Osteoporosis
• Fibrocystic lumps
• Night sweats
• Painful intercourse
• Insomnia
• Heart Palpitations
• Fatigue
• Hair Changes
• Heavy Bleeding

Prevent the symptoms of menopause purchase the Physicians' Select Breast Enhancement supplements that contain the all important phytoestrogens (click here for details). Mike, please link to the breast enhance pills cream order page.

Phytoestrogens through there natural balance of female hormones promote the development of glandular breast tissue. Most women taking herb containing these phytoestrogens notice a significant increase size, fullness and balance of their breast. Physicians' Select Herbal Breast Enhancement Supplements have herbs that are specifically known for their phytoestrogenic properties.

Please note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professionals. The information should not be construed to indicate that the use of the product is appropriate, safe, or effective for each individuals use. Individuals should consult with their healthcare professional prior taking any new product.

Phytoestrogen Information References:


Chlebowski, R. T. (2000). Reducing the risk of breast cancer. New England Journal of Medicine 343, 191-198.

Albertazzi, P. et al. The effect of dietary soy supplementation on hot flushes. Obstet Gynecol 1998 Jan; 91(1):6-11.

Medina, D., and Smith, G. H. (1999). Chemical carcinogen-induced tumorigenesis in parous, involuted mouse mammary glands. Journal of the National Cancer Institute 91, 967-969.

Brzezinski A, Debi A. Phytoestrogens: the "natural" selective estrogen receptor modulators? Eur J Obstet Gynecol Reprod Biol. 1999:85:47-51.

Consensus opinion: The role of isoflavones in menopausal health: consensus opinion of the North American Menopause Society. Menopause. 2000:7:21 5-229.

Andlauer, W., Kolb, J., and Furst, P. (2000). Isoflavones from tofu are absorbed and metabolized in the isolated rat small intestine. Journal of Nutrition 130, 3021-3027.

Lissin LW, Cooke JP. Phytoestrogens and cardiovascular health. J Am coll Cardiol. 2000:35:1403-1410.

Tham DM, Gardner CD. Haskell WL. Clinical review 97: Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence. J Clin Endocrinol Metab. 1998:83:2223-2235.

Wu, A. H., Stanczyk, F. Z., Hendrich, S., Murphy, P. A., Zhang, C., Wan, P., and Pike, M. C. (2000). Effects of soy foods on ovarian function in premenopausal women. British Journal of Cancer 82, 1879-1886.

Murkies AL. Wilcox G, Davis SR. Clinical Reviews 92 Phytoestrogens. J Clin Endocrinol Metab. 1998:83:297-303.

Xu, X., Duncan, A. M., Merz, B. E., and Kurzer, M. S. (1998). Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women. Cancer Epidemiology, Biomarkers, and Prevention 7, 1101-1108.

Hoffman, R. (1995). Potent inhibition of breast cancer cell lines by the isoflavonoid kievitone: comparison with genistein. Biochemical and Biophysical Research Communications 211, 600-606.

Baird, D. D. et al. Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women. J Clin Endocrinol Metab 1995 May; 80(5):1685-90.

Chiechi LM. Dietary phytoestrogens in the prevention of long-term postmenopausal diseases. Int J Gynaecol Obstet. 1999:67:39-40.