 
Source:
Phosphatidylserine - belongs to a special category of fat-soluble
substances called phospholipids, which are essential components
of cell membranes. Phosphatidylserine is found only in trace amounts
in the normal diet. Phosphatidylserine can be derived from a bovine
(cow) source, however, the form is not used secondary to the risk
of humans contracting "mad cow" disease. Currently, Phosphatidylserine
is derived from soy to prevent any spread of disease. |
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Physiology:
Brain cells are rich in Phosphatidylserine, which contributes to
these cells ability to release the chemical neurotransmitters. While
medications can increase the level of specific chemical neurotransmitters,
Phosphatidylserine improves the overall action of all the neurotransmitters
by enhancing the performance of cell membranes.
As an individual ages there are both biochemical and structural
changes in the brain. These changes include restructuring of the
neuronal membrane lipid composition, decreases in the metabolism
of neurotransmitters and a decrease in synaptic density. These changes
result in a decline in overall cognitive function i.e. decline in
memory, potential to learn new tasks and behavioral changes (loss
of motivation, socialization complications, increased anxiety, etc.).
Clinical Studies:
Clinical studies have shown that the supplemental use of Phosphatidylserine
produces significant improvement in memory, concentration, motivation,
anxiety and overall cognitive functioning. Individuals suffering
from Alzheimer's disease noted improvement on the Blessed Dementia
Scale (measure of information processing, activities of daily living,
memory). Phosphatidylserine also has a positive effect on individuals
who suffer from depression. Supplemental use of Phosphatidylserine
resulted in an improvement in depressive symptoms in as little as
thirty days of treatment.
Phosphatidylserine also appears to protect against the stress response
to reduce anxiety. Phosphatidylserine is especially effective when
combined with lifestyle revision, a healthy diet and proper exercise.
Modern day uses:
Today, Phosphatidylserine is prescribed by physicians and herbal
specialist for the following:
- Overall cognitive functioning including memory
and concentration
- Alzheimer's disease
- Depression
Precautions and/or adverse effects:
Individuals with preexisting medical conditions should consult with
their physician particularly if they are taking prescription or
over-the-counter-medications or supplements. Women who are pregnant
or breast feeding and children should also consult with there physician
prior to taking any new supplements There have been no significant
side effects or drug interactions with Phosphatidylserine presented
at the time of this writing. |
