Source:
Important for the normal function of many bodily processes, Niacin is directly and indirectly involved in over 50 different chemical reactions in the body including proper circulation, healthy supple skin, proper functioning of the nervous system, synthesis of the sex hormones, and assists in the breakdown and utilization of fats, proteins, carbohydrates and heavy metal detoxification. The vitamin can also help reduce the symptoms associated with Vertigo (the sensation of dizziness) Tinnitus (ringing or whistling stimulus in the ears), premenstrual syndrome (PMS), headaches, and osteoarthritis.

Like other B vitamins, Niacin is water-soluble and plays a role in turning food into energy, as well as in the metabolism of fats and carbohydrates. Niacin can also act as an antioxidant within cells, which means it can destroy cell-damaging free radicals. The best sources for Niacin in the diet including whole grains; organ meats (especially liver), carrots, brewer's yeast, legumes, fish, nuts, eggs, and green vegetables such as broccoli.

Physiology:
Niacin is important for the synthesis of the sex and adrenal hormones. Its primary sexual affect is from the side effect of the vitamin. Briefly after ingestion, niacin can produce sensations of intense warmth that quickly spreads throughout the body. This effect, is secondary to a release of histamine that produces a dilation of blood vessels and capillaries which results in subsequent increase in blood flow. The vasodilatation of the blood vessel is very similar to the flush felt instantaneously during sexual excitement and orgasms. The pleasurable feeling can last up to 20 minutes and because there is a larger than normal histamine release, the feeling is often more dramatic than the sensations that occur during intercourse.

Clinical Studies:
Niacin is also beneficial for individuals experiencing difficulty achieving orgasm. In a clinical study conducted by William Howell Masters and Virginia Eshelman Johnson (the most respected researchers in the field of sexuality) it was revealed that women could not achieve orgasm without having sufficient levels of niacin in the uterine walls. The ability to experience an orgasm correlated with the release of histamine, therefore, Niacin's ability to release large quantities of histamine has proved to be very beneficial to women who cannot experience orgasms. Niacin is also associated with intense sensations and increase in secretions in the mouth and sexual organs.

Modern day uses:
Niacin, vitamin B-3, is directly and indirectly involved in over 50 different chemical reactions in the body including the following:

• Proper circulation
• Healthy supple
• Proper functioning of the nervous system
• Digestion including secretion of bile
• Synthesis of the sex hormones
• Serve as a dopaminergic agonist for enhanced motor mechanism activity
• Plays an important role in energy production; fat, cholesterol and carbohydrate metabolism
• Treatment of schizophrenia
• Dilates the blood vessels (Flushing is a common positive side effect of vasodilatation caused by niacin)
• Assists in the breakdown and utilization of fats, proteins, and carbohydrates. and heavy metal detoxification
• The vitamin can also help reduce the symptoms associated with Vertigo (the sensation of dizziness) Tinnitus (A ring or whistling stimulus in the ears), premenstrual syndrome (PMS), headaches, and osteoarthritis.

Precautions and/or adverse effects:
Individuals with preexisting medical conditions should consult with their physician particularly if they are taking prescription or over-the-counter-medications or supplements. Women who are pregnant or nursing and children should also consult with their physician prior to taking any new supplements.

When taken as a dietary supplement, the resulting Niacin flush is considered a harmless side effect. However, secondary to Niacin's acid properties (nicotinic acid), higher doses can contribute to acid indigestion by releasing excessive histamine in the stomach. Individuals with diabetes, active ulcers, B vitamin allergy, kidney or liver impairment, severe hypotension, unstable angina, arterial hemorrhage, coronary artery disease, peptic ulcers, undergoing drug treatment for tuberculosis, using transdermal nicotine, and Carbamazepine (an anti-seizure medication), should refrain from taking Niacin without first consulting with their physician and/or pharmacists.