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  Human Growth Hormone HGH Information

The following represents a summary of how Human Growth Hormone, HGH influences physiological processes to promote a youthful vigor:

HGH or Human Growth Hormone (also called somatotrophin) is produced in the anterior of the pituitary gland deep inside the brain, where it is one of the most abundant hormones secreted.

It influences the growth of cells, bones, muscles and organs throughout the body. Production peaks at adolescence when accelerated growth occurs. If growing children have too little they remain as dwarfs, while if they have too much they become giants.

HGH is one of many endocrine hormones, like estrogen, progesterone, testosterone, melatonin and DHEA, that all decline in production with age. While many of these hormones can be replaced to deter some of the effects of aging, HGH reaches far beyond the scope of any of these hormones.

Not only does it prevent biological aging, but also it acts to significantly reverse a broad range of the signs and symptoms associated with the aging process.

Human Growth Hormone is a polypeptide hormone composed of a long chain of 191 amino acids. Under normal physiologic conditions, Growth Hormone is secreted by the anterior pituitary gland. This is a gland that lies at the base of the brain in a bony cavity called the Sella Turcica. In addition to Growth Hormone, the anterior pituitary also secretes prolactin, follicle stimulating hormone, thyroid stimulating hormone, luteinizing hormone and adrenal corticotropic hormone.

The secretion of Growth Hormone by the pituitary gland is initiated by the hypothalamus, another gland in the brain that lies right next to the pituitary. The hypothalamus initiates Growth Hormone secretion by secreting Growth Hormone releasing hormone (GHRH); at the same time it stops secreting a Growth Hormone inhibitory hormone called somatostatin. When somatostatin is turned off and GHRH is turned on, the pituitary will release Growth Hormone in different bursts of activity. These bursts of Growth Hormone release occur primarily during deep stages of sleep, such as stage 3 and stage 4. Once released in the blood, Growth Hormone is very short lived. In fact, HGH or Human Growth Hormone is generally completely metabolized and gone within a half-hour. During this period, however, Human Growth Hormone manages to reach the liver and many other cells in the body, and induce them to make another polypeptide hormone called Insulin-like Growth Factor One (IGF-1). It is really IGF-1 that travels around to the various tissues of the body to effect most of the benefits that we attribute to Growth Hormone.

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The secretion of Growth Hormone itself is regulated by a classic biofeedback loop. Hence when levels of Growth Hormone in the blood reach a certain threshold, Growth Hormone stimulates receptors in the pituitary to stop further Growth Hormone secretion. It also stimulates receptors in the hypothalamus to stop GHRH and turn on somatostatin. IGF-1, which goes up in response to Growth Hormone, also feeds back on the pituitary and hypothalamus to help control Growth Hormone secretion.

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Growth Hormone plays a major in stimulating body growth by signaling the liver and other tissues to secrete IGF-1:


In addition, Growth Hormone has important effects on carbohydrate lipid (fat) and protein metabolism:

  • Carbohydrate metabolism - Growth Hormone is one of the many hormones that serves to maintain blood glucose within a normal range. Growth hormone is often said to have anti-insulin activity, because it supresses the abilities of insulin to stimulate uptake of glucose in peripheral tissues and enhance glucose synthesis in the liver.
  • Lipid (fat) metabolism - Growth Hormone enhances the utilization of fat by stimulating triglyceride breakdown and oxidation in adipocytes. Fat cells (adipocytes)have Growth Hormone receptors. Growth Hormone stimulates these receptors to cause the break down of triglycerides suppressing their ability to absorbed.
  • Protein metabolism - Growth Hormone stimulates protein synthesis in many tissues. This results in increased amino acid uptake.


Decline in Human Growth Hormone with age

Human Growth Hormone is secreted by the pituitary gland were the Human Growth Hormone levels peak during adolescence. Human Growth hormone levels subsequently decreases with age. The levels of human Growth Hormone after age 30 declines approximately 15% per decade. Generally, we produce approximately 500 micrograms of human Growth Hormone daily at age twenty, 200 micrograms at age forty, and only 25 micrograms at age eighty. Secondary to the natural decrease in human Growth Hormone production by age forty we are producing only some forty percent of what we produced at age twenty. Now with advent of Human Growth Hormone supplements like Physicians' Select Human Growth Hormone Supplements we can now see markedly increased levels of Human Growth Hormone.

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Fortunately, with the advances in science we can now increase human Growth Hormone levels. Secondary to increasing Growth Hormone levels we can now expect a much improved quality of life including the following:
Increase libido and sexual performance - HGH acts as a powerful aphrodisiac. Human Growth Hormone also restores sexual potency and sexuality in men. Many of the women who use it also report increased libido and heightened pleasure. It also helps to alleviate menstrual and post-menopausal symptoms.
Weight Loss - increases in the metabolism to former highs selectively reducing fat deposits in the area of the abdomen, hips, waist and thighs. Subjects in the Rudman study experienced a 14.4% decrease in body fat and an increase in lean muscle mass of 8.8%, all within months.
Lipid (fat) metabolism - Human Growth Hormone enhances the utilization of fat by stimulating triglyceride breakdown and oxidation in fat cells. Fat cells (adipocytes) have Growth Hormone receptors. Human Growth Hormone stimulates these receptors to cause the break down of triglycerides suppressing their ability to absorbed, promoting weight loss.
Increases energy - Human Growth Hormone can have a profound effect on increasing energy and a sense of well-being. Human Growth Hormone can reinvigorate the mind and also reverse the attitudes and expectations associated with aging. These properties also result in an improved level of self confidence.
Improves exercise and muscle mass - medical studies have shown that positive results occur only while Human Growth Hormone is being secreted by the body. Human Growth Hormone significantly increases the effects of exercise and muscle mass including: energy, stamina, endurance and muscle strength.
Heightens libido and sexual performance - acts as a powerful aphrodisiac. Human Growth Hormone also restores sexual potency and sexuality in both men and women. Many of the women who use Human Growth Hormone Supplement also report increased libido and heightened orgasms. HGH also helps to alleviate menstrual and post-menopausal symptoms.
Cardiovscular system - increased levels of Human Gowth Hormone as shown to lower blood pressure and decrease cholesterol decreasing the risks for heart attacks, strokes, etc.
Improved skin - Human Growth Hormone hydrates the skin resulting in more elastic and supple appearance. In addition, the hydration reduces the fine lines and wrinkles that are associated with aging skin.
Hair and nails - HGH appears to have a tonic effect on hair. In clinical trials some 38% of individuals reported new hair growth(hair coming in faster), thicker more natural hair with a return to the natural color. Nails also become thicker and stronger.
Brain and memory - the brain and nervous system are made up of cells called neurons, which are permanent and never regenerate. However, Human Growth Hormone can stimulate the repair and rejuvenation of these cells. HGH also affects the proteins produced in the brain for storing memory. Therefore, learning, memory and intelligence all depend on adequate supplies of Human Growth Hormone.
Sleep patters - clinical studies have shown that individuals using Human Growth Hormone report improved sleep patterns. These individuals also report waking up energized and refreshed ready to address the days challenges.
Antioxidant cell protection - Human Growth Hormone acts on proteases (the destructive enzymes that cause cell damage). HGH activates a cellular defense called protease inhibitors, which prevent free radicals from destroying healthy cells. Research shows that Human Growth Hormone also can also improve the effects of antioxidants.
Immune responce booster - Human Growth Hormone increases the action of the immune system. Secondary to this action, Human Growth Hormone is becoming a standard regimen in the treatment of individuals who have a deficiency in their immune response.

Please note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. The information should not be construed to indicate that the use of the product is appropriate, safe, or effective for each individuals use. Individuals should consult their healthcare professional prior taking any new product.

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