Source:
L Arginine - is an essential amino acid (the body cannot create
the amino acid on its own it must be ingested). Arginine is found
in many foods, including dairy products, meat, fish and poultry. |
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How L Arginine Increase Blood Flow to the Penis
(Better erections with L Arginine in the
corpus cavernosum)
Physiology:
L-arginine promotes the erection process by acting
as a precursor to the formation of nitrous oxide. During the normal
male erection process blood flow is directed into the corpus cavernosum.
The corpus cavernosum consists of “sponge like” tissue which runs
the length of the penis. As the corpus cavernosum fills with blood,
it expands and begins to press against the body of the penis. This
pressure closes the veins reducing their ability to carry blood
away from the penis. The reduction in venous blood flow, known as
venous occlusion, allows blood to be trapped in the corpus cavernosum.
This process continues until the pressure in the corpus cavernosum
equals the pressure of the corpus cavernosal arteries. It is at
this point that the penis is fully erect. |
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The engorgement of the corpus cavernosum and subsequent erection
is triggered by a short-lived neurotransmitter, nitric oxide. Nitric
oxide is synthesized from the oxidation of the amino acid L arginine.
In order to produce nitric oxide in the body, a terminal nitrogen
atom must combine with an oxygen molecule in the blood. An enzyme
called nitric oxide synthase controls this reaction and NADPH, niacin-containing
redox-active electron storage compound, mediates the reaction. This
reaction can be accomplished via oral ingestion of formulas that
contain the free form amino acid L-arginine. The left-handed molecule,
L-arginine, is the primary source for Nitric Oxide in humans.
Once synthesized nitrous oxide activates an enzyme
that manufactures cyclic guanosine monophosphate (cGMP), a biochemical
signaling enzyme. The cGMP, directs the smooth muscle cells to relax,
leading to the dilation of penile arteries and the subsequent filling
of the corpus cavernosum. Immediately following the release of nitrous
oxide and production of cGMP, another enzyme, cGMP phosphodiesterase
Type 5 named PDE-5, is activated. PDE-5’s main activity is to break
down cGMP almost as fast as it is formed. The result of this breakdown
of cGMP by PDE-5 is a rapid decrease in smooth muscle relaxation
and a loss of blood flow to the penis. Subsequently, the penis returns
to its flaccid state.
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Clinical Studies:
L-arginine through its oxidation process to nitric
oxide,
plays a significant role in the erection process. Research has shown
that increased levels of nitric oxide can correct up to 90% of the
clinical cases of erectile dysfunction. The role of nitric oxide
in controlling blood flow was only recently discovered in 1998 resulting
in a Nobel Prize for scientific discovery. From this discovery,
the researchers at Physicians’ Select further researched the importance
of L-Arginine in our male libido enhancer supplement to promote
the optimal male sexual response.
Modern day uses:
In addition to promoting the erectile response L arginine also is
beneficial in the following ways:
- Necessary for spermatogenesis
- Precursor amino acid to human growth hormone
- Essential for normal immune system activity
- Promotes muscle growth and fat burning
- Assists with regeneration of damaged liver
- Necessary for production and release of growth hormone
- A precursor to Creatine and the neurotransmitter nitric oxide
- Arginine is crucial to the wound healing process through collagen
synthesis, particularly in the elderly who suffer from poor circulation
- Arginine is the most potent amino acid in releasing insulin.
- Precursor to GABA, an important inhibitory neurotransmitter
- Improves immune response to bacteria, viruses, and tumor cells
- Supplementation of the amino acid can reduce the pathological
increases in the thickness of plaque lined vessel walls in individuals
with elevated cholesterol and arthrosclerosis
Precautions and/or adverse effects:
Individuals with preexisting medical conditions should consult with
their physician particularly if they are taking prescription or
over-the-counter-medications or supplements. Women who are pregnant
or breast feeding and children should also consult with there physician
prior to taking any new supplements.
More specifically, individuals
should not take Arginine supplements if they are predisposed to
any the following medical conditions:
- Cancer
- Low blood pressure
- Liver or Kidney disease
- Individuals on blood thinners
- Psychological conditions, such as, psychosis
- Diabetics and borderline diabetics
- Individuals who have not completed their bone growth i.e. children
and/or teenagers
- Individuals with acute or chronic viral conditions i.e. Epstein-Barr
Virus (EBV),
- Cytomegalovirus (CMV), Herpes Virus, Human Immunodeficiency
Virus (HIV)
There are very few side effects associated with
the supplemental use of the herb. Though, individuals may experience
an increase in cold sores or herpetic lesions (increase doses
of arginine may promote the outbreak if herpes simplex in individuals
who have the virus). Excessive
dosage
of arginine may also cause diarrhea, stomach cramps, bloating, swelling
in the lower extremities.
Enhance your
erections with a Better Erection Supplement that contains L Arginine Physicians
Select Better Erection Pills (click here for details).
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General
Herbal Information
